Efficient 1,2-Addition of Aryl- and Alkenylboronic Acids to Aldehydes Catalyzed by the Palladium/Thioether-Imidazolinium Chloride System
Masami Kuriyama,* Rumiko Shimazawa and Ryuichi Shirai*
*Faculty of Pharmaceutical Sciences, Doshisha Women's College
of Liberal Arts, Kodo, Kyotanabe, Kyoto 610-0395, Email: mkuriyam
dwc.doshisha.ac.jp,
rshiraidwc.doshisha.ac.jp
M. Kuriyama, R. Shimazawa, R. Shirai, J. Org. Chem., 2008, 73, 1597-1600.
DOI: 10.1021/jo7020983
Abstract
The use of a thioether-imidazolinium chloride as a heterobidentate carbene ligand precursor led to a high level of catalyst performance in the palladium-catalyzed 1,2-addition of aryl-, heteroaryl-, and alkenylboronic acids to aromatic, heteroaromatic, and aliphatic aldehydes.
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Key Words
Benzylic Alcohols, Allylic Alcohols
ID: J42-Y2008-0490
