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H2O2/Tf2O System: An Efficient Oxidizing Reagent for Selective Oxidation of Sulfanes

Mohammad Mehdi Khodaei*, Kiumars Bahrami*, Ahmad Karimi

*Department of Chemistry, Razi University, Kermanshah 67149, Iran, Email:,

M. M. Khodaei, K. Bahrami, A. Karimi, Synthesis, 2008, 1682-1684.

DOI: 10.1055/s-2008-1067019


A versatile procedure oxidizes sulfanes to sulfoxides without any overoxidation to sulfones using a combination of hydrogen peroxide and triflic acid. This method tolerates oxidatively sensitive functional groups.

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TAPC-Promoted Oxidation of Sulfides and Deoxygenation of Sulfoxides

K. Bahrami, M. M. Khodaei, M. S. Arabi, J. Org. Chem., 2010, 75, 6208-6213.

Key Words

sulfoxides, hydrogen peroxide, triflic anhydride, chemoselectivity, environmentally friendly

ID: J66-Y2008-1440