Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides
Feng Shi, Jesse P. Waldo, Yu Chen and Richard C. Larock*
*Department of Chemistry, Iowa State University, Ames, Iowa
50010, Email: larock
iastate.edu
F. Shi, J. P. Waldo, Y. Chen, R. C. Larock, Org. Lett., 2008, 10, 2409-2412.
DOI: 10.1021/ol800675u (free Supporting Information)
Abstract
A [3 + 2] cycloaddition of azides to benzynes affords a rapid and easy entry to a variety of substituted, functionalized benzotriazoles under mild conditions.
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Key Words
Benzotriazoles, Click Chemistry, 1,3-dipolar Cycloaddition
ID: J54-Y2008-1590
