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Efficient Sonogashira Coupling Reaction Catalyzed by Palladium(II) β-Oxoiminatophosphane Complexes under Mild Conditions

Dong-Hwan Lee, Huili Qiu, Min-Ho Cho, Ik-Mo Lee, Myung-Jong Jin*

*Department of Chemical Engineering and Chemistry, Inha University, Incheon 402-751, Korea, Email: mjjininha.ac.kr

D.-H. Lee, H. Qiu, M.-H. Cho, I.-M. Lee, M.-J. Jin, Synlett, 2008, 1657-1660.

DOI: 10.1055/s-2008-1077873


Abstract

In the presence of very low amounts of palladium(II) β-oxoiminatophosphane complexes, various aryl iodides and bromides were efficiently coupled with terminal alkynes at low temperatures. The mild, efficient, aerobic, solvent-free, and copper-free conditions also allowed Sonosgahira reactions of aryl chlorides.

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Key Words

palladium, β-oxoiminatophosphanes, catalysis, arylated alkynes, Sonogashira reaction


ID: J60-Y2008-1790