Copper-Catalyzed Sonogashira-Type Reactions Under Mild Palladium-Free Conditions
Florian Monnier*, François Turtaut, Leslie Duroure and Marc Taillefer*
*École Nationale Supérieure de Chimie de Montpellier,
Institut Charles Gerhardt Montpellier, CNRS UMR 5253, Architectures Moléculaires
et Matériaux Nanostrucuturs, 8 rue de l’Ecole Normale, 34296 Montpellier, Cedex
05 France, Email: florian.monnier
enscm.fr, marc.tailleferenscm.fr
F. Monnier, F. Turtaut, L. Duroure, M. Taillefer, Org. Lett., 2008, 10, 3203-3206.
DOI: 10.1021/ol801025u (free Supporting Information)
Abstract
An inexpensive catalytic system using a readily available copper/ligand combination for the Sonogashira-type cross-coupling of aryl iodides and phenyl- and hexyl-acetylene affords disubstituted alkynes in good yields.
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Key Words
ID: J54-Y2008-2100
