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Aza-Henry Reaction of Ketoimines Catalyzed by Na2CO3: An Efficient Way to β-Nitroamines

Liwei Wang, Cheng Tan, Xiaohua Liu, Xiaoming Feng*

*Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. of China, Email: xmfengscu.edu.cn

L. Wang, C. Tan, X. Liu, X. Feng, Synlett, 2008, 2075-2077.

DOI: 10.1055/s-2008-1077952 (free Supporting Information)


Abstract

In the presence of only 5 mol% Na2CO3, N-tosyl ketoimines can react with nitromethane to give β-nitroamines via aza-Henry reaction in very good yields in THF at room temperature.

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Key Words

aza-Henry reaction, inorganocatalyst, ketoimines, nitromethane, β-nitroamines, nitro compounds


ID: J60-Y2008-2230