Ruthenium Hydride-Catalyzed Addition of Aldehydes to Dienes Leading to β,γ-Unsaturated Ketones
Sohei Omura, Takahide Fukuyama, Jiro Horiguchi, Yuji Murakami and Ilhyong Ryu*
*Department of Chemistry, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan, Email: ryuc.s.osakafu-u.ac.jp
S. Omura, T. Fukuyama, J. Horiguchi, Y. Murakami, I. Ryu, J. Am. Chem. Soc., 2008, 130, 14094-14095.
DOI: 10.1021/ja806929y
see article for more reactions
Abstract
An efficient cross-addition reaction of dienes with aldehydes in the presence of RuHCl(CO)(PPh3)3 as catalyst gives various β,γ-unsaturated ketones. A π-allylruthenium species, derived from hydroruthenation of the diene, may be involved as a key intermediate.
see article for more examples
Key Words
ID: J48-Y2008-3090