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Ruthenium Hydride-Catalyzed Addition of Aldehydes to Dienes Leading to β,γ-Unsaturated Ketones

Sohei Omura, Takahide Fukuyama, Jiro Horiguchi, Yuji Murakami and Ilhyong Ryu*

*Department of Chemistry, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan, Email: ryuc.s.osakafu-u.ac.jp

S. Omura, T. Fukuyama, J. Horiguchi, Y. Murakami, I. Ryu, J. Am. Chem. Soc., 2008, 130, 14094-14095.

DOI: 10.1021/ja806929y


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Abstract

An efficient cross-addition reaction of dienes with aldehydes in the presence of RuHCl(CO)(PPh3)3 as catalyst gives various β,γ-unsaturated ketones. A π-allylruthenium species, derived from hydroruthenation of the diene, may be involved as a key intermediate.

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Key Words

Allyl Ketones


ID: J48-Y2008-3090