Efficient Negishi Coupling Reactions of Aryl Chlorides Catalyzed by Binuclear and Mononuclear Nickel-N-Heterocyclic Carbene Complexes
Zhenxing Xi, Yongbo Zhou and Wanzhi Chen*
*Department of Chemistry, Zhejiang University, Xixi Campus, Hangzhou 310028, P. R. China, Email: chenwzzzju.edu.cn
Z. Xi, Y. Zhou, W. Chen, J. Org. Chem., 2008, 73, 8497-8501.
DOI: 10.1021/jo8018686 (free Supporting Information)
Mononuclear and binuclear nickel-NHC complexes supported by heteroarene-functionalized NHC ligands are highly efficient catalysts for the coupling of unactivated aryl chlorides and organozinc reagents, leading to biaryls in good to excellent yields under mild conditions.
see article for more examples