An Efficient Method for the Selective Iodination of α,β-Unsaturated Ketones
Zihua Wang, Guodong Yin, Jing Qin, Meng Gao, Liping Cao, Anxin Wu*
*Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Central China Normal University, Wuhan 430079, P. R. of China, Email: chwuaxmail.ccnu.edu.cn
Z. Wang, G. Yin, J. Qin, M. Gao, L. Cao, A. Wu, Synthesis, 2008, 3565-3568.
An efficient approach to α,β-unsaturated α′-iodo ketones directly from α,β-unsaturated ketones by selective iodination at the α′-position in the presence of copper(II) oxide/iodine offers high yields, short reaction times, inexpensive reagents, mild reaction conditions, ease of manipulation, and the formation of cleaner products.
see article for more examples