Oxidative Pd(II)-Catalyzed C-H Bond Amination to Carbazole at Ambient Temperature
James A. Jordan-Hore, Carin C. C. Johansson, Moises Gulias, Elizabeth M. Beck and Matthew J. Gaunt*
*Department of Chemistry, University of Cambridge, Lensfield
Road, Cambridge, CB2 1EW, U.K., Email: mjg32
cam.ac.uk
J. A. Jordan-Hore, C. C. C. Johansson, M. Gulias, E. M. Beck, M. J. Gaunt, J. Am. Chem. Soc., 2008, 130, 16184-16186.
DOI: 10.1021/ja806543s
Abstract
A Pd(II)-catalyzed C-H bond amination reaction operates under extremely mild conditions and produces carbazole products in good to excellent yields. Carbazoles possessing complex molecular architecture can also be formed using this reaction, highlighting its potential in natural product synthesis applications.
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Key Words
carbazoles, phenyliodonium diacetate
ID: J48-Y2008-3550
