[(NHC)AuI]-Catalyzed Acid-Free Alkyne Hydration at Part-per-Million Catalyst Loadings
Nicolas Marion, Rubén S. Ramón and Steven P. Nolan*
*School of Chemistry, University of St Andrews, St Andrews KY16 9ST, U.K., Email: sn17st-andrews.ac.uk
N. Marion, R. S. Ramón, S. P. Nolan, J. Am. Chem. Soc., 2009, 131, 448-449.
DOI: 10.1021/ja809403e
Abstract
A highly efficient [(NHC)AuCl]-based catalytic system allows the hydration of terminal and internal alkynes possessing any combination of alkyl and aryl substituents under acid-free conditions and at very low catalyst loadings.
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ID: J48-Y2009-0290