Desulfurization of Thioamides into Amides with H2O2/ZrCl4 Reagent System
Kiumars Bahrami*, Mohammad Mehdi Khodaei*, Yeganeh Tirandaz
*Department of Chemistry, Razi University, Kermanshah 67149, Iran, Email: kbahrami2hotmail.com, mmkhodarazi.ac.ir
K. Bahrami, M. M. Khodaei, Y. Tirandaz, Synthesis, 2009, 369-371.
The hydrogen peroxide-zirconium(IV) chloride reagent system is efficient and general for the conversion of thioamides to amides in short reaction times and good chemoselectivity, and allows a simple workup that precludes the use of toxic solvents.
see article for more examples
K. Bahrami, M. M. Khodaei, M. Tajik, Synthesis, 2010, 4282-4286.