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An Efficient Route to 1-Vinylpyrrole-2-carbaldehydes

Al'bina I. Mikhaleva, Andrey V. Ivanov, Elena V. Skital'tseva, Igor' A. Ushakov, Alexander M. Vasil'tsov, Boris A. Trofimov*

*A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 1 Favorsky Street, 664033 Irkutsk, Russian Federation, Email:

A. I. Mikhaleva, A. V. Ivanoc, E. V. Skital'tseva, I. A. Ushakov, A. M. Vasil'tsov, B. A. Trofimov, Synthesis, 2009, 587-590.

DOI: 10.1055/s-0028-1083312


1-Vinylpyrroles are formylated by the N,N-dimethyl­formamide/oxalyl chloride reagent system to give the corresponding 1-vinylpyrrole-2-carbaldehydes in good yields in short reaction times.

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Key Words

aldehydes, pyrroles, formylation, oxalyl chloride, Vilsmeier-Haack reaction

ID: J66-Y2009-0470