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Daucus carota Mediated-Reduction of Cyclic 3-Oxo-amines

Romain Lacheretz, Domingo Gomez Pardo and Janine Cossy*

*Laboratoire de Chimie Organique, ESPCI ParisTech, CNRS, 10 rue Vauquelin, 75231-Paris Cedex 05, France, Email: janine.cossyespci.fr

R. Lacheretz, D. G. Pardo, J. Cossy, Org. Lett., 2009, 11, 1245-1248.

DOI: 10.1021/ol8029214 (free Supporting Information)


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Abstract

Carrots (Daucus carota) were used as cheap, eco-compatible, and efficient reducing reagent for the conversion of cyclic amino-ketones into amino-alcohols in high yields and enantiomeric excesses. The procedure allows an easy access to precursors of biologically active products.

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Key Words

Carrots, Reduction of Carbonyl Compounds


ID: J54-Y2009-0830