Organic Chemistry Portal

Abstracts

Search:

Two Titanium-Catalyzed Reaction Sequences for Syntheses of Pyrroles from (E/Z)-Chloroenynes or α-Haloalkynols

Lutz Ackermann*, René Sandmann and Ludwig T. Kaspar

*Institut für Organische and Biomolekulare Chemie, Georg-August-Universität, Tammannstrasse 2, 37077 Göttingen, Germany, Email: lutz.ackermannchemie.uni-goettingen.de

L. Ackermann, R. Sandmann, L. T. Kaspar, Org. Lett., 2009, 11, 2031-2034.

DOI: 10.1021/ol900522g (free Supporting Information)


Abstract

Titanium-catalyzed intermolecular hydroaminations enabled efficient, user-friendly one-pot reactions for the preparations of 2-substituted and fully substituted pyrroles from (E/Z)-chloroenynes and easily accessible α-haloalkynols, respectively.

see article for more examples



Key Words

Pyrroles


ID: J54-Y2009-1420