Metal-Brønsted Acid Cooperative Catalysis for Asymmetric Reductive Amination
Chaoqun Li, Barbara Villa-Marcos and Jianliang Xiao*
*Liverpool Centre for Materials and Catalysis, Department of
Chemistry, University of Liverpool, Liverpool L69 7ZD, U.K., Email: j.xiao
liv.ac.uk
C. Li, B. Villa-Marcos, J. Xiao, J. Am. Chem. Soc., 2009, 131, 6967-6969.
DOI: 10.1021/ja9021683
Abstract
Cooperative catalysis of an Ir(III)-diamine complex and a chiral phosphoric acid or its conjugate base enables a direct reductive amination of a wide range of ketones.
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Key Words
reductive amination, aryl amines, hydrogen
ID: J48-Y2009-1590
