Organic Chemistry Portal

Abstracts

Search:

A Convenient Synthesis of 1-Substituted 1,2,3-Triazoles via CuI/Et3N Catalyzed ‘Click Chemistry' from Azides and Acetylene Gas

Lu-Yong Wu, Yong-Xin Xie, Zi-Sheng Chen, Yan-Ning Niu, Yong-Min Liang*

*State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. of China, Email: liangymlzu.edu.cn

L.-Y. Wu, Y.-X. Xie, Z.-S. Chen, Y.-N. Niu, Y.-M. Liang, Synlett, 2009, 1453-1456.

DOI: 10.1055/s-0029-1216745 (free Supporting Information)


Abstract

1-Substituted-1,2,3-triazoles were conveniently synthesized from the corresponding aromatic and aliphatic azides in the presence of acetylene gas using mild, copper(I)-catalyzed ‘click chemistry'.

see article for more examples



Key Words

azides, copper catalysis, click chemistry, acetylene gas, 1,2,3-triazoles


ID: J60-Y2009-1690