Syntheses of Substituted Furans and Pyrroles by Platinum-Catalyzed Cyclizations of Propargylic Oxiranes and Aziridines in Aqueous Media
Masahiro Yoshida*, Mohammad Al-Amin, Kozo Shishido
*Graduate School of Pharmaceutical Sciences, The University
of Tokushima, 1-78-1 Sho-machi, Tokushima 770-8505, Japan, Email: yoshida
ph.tokushima-u.ac.jp
M. Yoshida, M. Al-Amin, K. Shishido, Synthesis, 2009, 2454-2466.
DOI: 10.1055/s-0029-1216867
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Abstract
Highly substituted furans were conveniently synthesized by the platinum-catalyzed reaction of propargylic oxiranes. Propargylic aziridines were also reacted with the platinum catalyst to produce the corresponding substituted pyrroles in good yields.
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Key Words
alkynes, epoxides, furans, platinum, pyrroles
ID: J66-Y2009-2180
