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Triazole-Au(I) Complexes: A New Class of Catalysts with Improved Thermal Stability and Reactivity for Intermolecular Alkyne Hydroamination

Haifeng Duan, Sujata Sengupta, Jeffrey L. Petersen, Novruz G. Akhmedov and Xiaodong Shi*

*C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, Email: xmshiusf.edu

H. Duan, S. Sengupta, J. L. Petersen, N. G. Akhmedov, X. Shi, J. Am. Chem. Soc., 2009, 131, 12100-12102.

DOI: 10.1021/ja9041093 (free Supporting Information)


Abstract

1,2,3-triazole-bound cationic Au(I) catalysts possess much better thermal stability than literature-reported Au catalysts, including IPrAu•NTf2. By application of these catalysts, challenging intermolecular hydroaminations were achieved with less-reactive internal alkynes and unprotected aliphatic amines, giving excellent yields with low catalyst loading.

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Key Words

Arylamines, Borane


ID: J48-Y2009-2600