Organic Chemistry Portal

Abstracts

Search:

Catalytic Direct Arylations in Polyethylene Glycol (PEG): Recyclable Palladium(0) Catalyst for C-H Bond Cleavages in the Presence of Air

Lutz Ackermann* and Rubén Vicente

*Institut fuer Organische und Biomolekulare Chemie, Georg-August-Universitaet, Tammannstrasse 2, 37077 Goettingen, Germany, Email: lutz.ackermannchemie.uni-goettingen.de

L. Ackermann, R. Vicente, Org. Lett., 2009, 11, 4922-4925.

DOI: 10.1021/ol9020354 (free Supporting Information)


see article for more reactions

Abstract

The use of nontoxic polyethylene glycol (PEG) as solvent and MesCO2H as cocatalyst enabled user-friendly palladium(0)-catalyzed C-H bond functionalizations under air in the absence of phosphine ligands. Direct arylations of 1,2,3-triazoles gave substituted triazoles in good yields. Recycling of the catalytic system led to a slight decrease of activity.

see article for more examples



Key Words

1,2,3-Triazoles, Heterobiaryls


ID: J54-Y2009-3180