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Synthetic Approach to Polysubstituted Furans: An Efficient Addition/Oxidative Cyclization of Alkynoates and 1,3-Dicarbonyl Compounds

Weibing Liu, Huanfeng Jiang*, Min Zhang and Chaorong Qi

*School of Chemistry and Chemical Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China, Email: jianghfscut.edu.cn

W. Liu, H. Jiang, M. Zhang, C. Qi, J. Org. Chem., 2010, 75, 966-968.

DOI: 10.1021/jo902375k (free Supporting Information)


Abstract

A reliable method for the direct construction of polysubstituted furans involves Sn(II)- and Cu(I)-promoted addition/oxidative cyclization of alkynoates and 1,3-dicarbonyl compounds in the presence of 2,3-dichloro-5,6-dicyanobenzoquinone.

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Copper-Catalyzed Domino Rearrangement/Dehydrogenation Oxidation/Carbene Oxidation for One-Pot Regiospecific Synthesis of Highly Functionalized Polysubstituted Furans

H. Cao, H. Jiang, W. Yao, X. Liu, Org. Lett., 2009, 11, 1931-1933.


Key Words

Furans, DDQ


ID: J42-Y2010-0360