K-10-Catalyzed Highly Diastereoselective Synthesis of Aziridines
Dmitry Borkin, Alena Carlson, Béla Török*
*Department of Chemistry, University of Massachusetts Boston,
100 Morrissey Blvd. Boston, MA 02125, USA, Email: bela.torok
umb.edu
D. Borkin, A. Carlson, B. Török, Synlett, 2010, 745-748.
DOI: 10.1055/s-0029-1219361
Abstract
Montmorillonite K-10 as solid acid catalyzes a stereoselective reaction of imines with ethyl diazoacetate to yield cis-aziridines. The reactions proceeded readily at room temperature in short reaction times, providing the products in very good yields and exclusive selectivity.
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Key Words
montmorillonite K-10, imines, aziridines, ethyl diazoacetate, heterogeneous catalysis, green chemistry
ID: J60-Y2010-0650
