Synthesis of 2H-Indazoles by the [3 + 2] Cycloaddition of Arynes and Sydnones
Chunrui Wu, Yuesi Fang, Richard C. Larock* and Feng Shi
*Department of Chemistry, Iowa State University, Ames, Iowa 50010, Email: larockiastate.edu
C. Wu, Y. Fang, R. C. Larock, F. Shi, Org. Lett., 2010, 12, 2171-2173.
DOI: 10.1021/ol100586r (free Supporting Information)
A rapid and efficient synthesis of 2H-indazoles, which involves a [3 + 2] dipolar cycloaddition of arynes and sydnones, proceeds under mild reaction conditions in good to excellent yields.
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Z. Liu, F. Shi, P. D. G. Martinze, C. Raminelli, R. C. Larock, J. Org. Chem., 2008, 73, 219-226.