Sulfur Modification of Au via Treatment with Piranha Solution Provides Low-Pd Releasing and Recyclable Pd Material, SAPd
Naoyuki Hoshiya, Masahiko Shimoda, Hideki Yoshikawa, Yoshiyuki Yamashita, Satoshi Shuto and Mitsuhiro Arisawa*
*Faculty of Pharmaceutical Sciences, Hokkaido University,
Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812 Japan, Email: arisawa
pharm.hokudai.ac.jp
N. Hoshiya, M. Shimoda, H. Yoshikawa, Y. Yamashita, S. Shuto, M. Arisawa, J. Am. Chem. Soc., 2010, 132, 7270-7272.
DOI: 10.1021/ja9100084
Abstract
Palladium immobilized on a sulfur-modified gold surface (SAPd) offers a high recyclability. Because this material leaches extremely low levels of Pd into the reaction mixture, removal of the residual Pd is unnecessary using SAPd, even in syntheses involving pharmaceutical ingredients.
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Key Words
Suzuki Coupling, Biaryls, Green Chemistry
ID: J48-Y2010-1510
