CuH-Catalyzed Enantioselective 1,2-Reductions of α,β-Unsaturated Ketones
Ralph Moser, Žarko V. Bošković, Christopher S. Crowe and Bruce H. Lipshutz*
*Department of Chemistry and Biochemistry, University of
California, Santa Barbara, California 93106, Email: lipshutz
chem.ucsb.edu
R. Moser, Ž. V. Bošković, C. S. Crowe, B. H. Lipshutz, J. Am. Chem. Soc., 2010, 132, 7852-7853.
DOI: 10.1021/ja102689e
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Abstract
Asymmetric ligand-accelerated catalysis by copper hydride allows the synthesis of valued nonracemic allylic alcohols in very good yields.
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Key Words
1,2-Reduction, Silanes, Copper Hydride
ID: J48-Y2010-1610
