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A General Palladium Catalyst System for Suzuki-Miyaura Coupling of Potassium Aryltrifluoroborates and Aryl Mesylates

Wing Kin Chow, Chau Ming So, Chak Po Lau and Fuk Yee Kwong*

*State Key Laboratory of Chiroscience and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, Email: bcfykinet.polyu.edu.hk

W. K. Chow, C. M. So, C. P. Lau, F. Y. Kwong, J. Org. Chem., 2010, 75, 5109-5112.

DOI: 10.1021/jo100846t (free Supporting Information)


Abstract

A palladium-catalyzed Suzuki-type cross-coupling of aryl and heteroaryl mesylates with potassium aryl and heteroaryltrifluoroborates gives biaryls in good yields. In addition, cross-coupling reactions of aryl mesylates with alkyl and vinyltrifluoroborate salts have also been successfully accomplished.

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Suzuki-Miyaura Coupling of Aryl Tosylates Catalyzed by an Array of Indolyl Phosphine-Palladium Catalysts

C. M. So, C. P. Lau, A. S. C. Chan, F. Y. Kwong, J. Org. Chem., 2008, 73, 7731-7734.

Palladium-Indolylphosphine-Catalyzed Hiyama Cross-Coupling of Aryl Mesylates

C. M. So, H. W. Lee, C. P. Lau, F. Y. Kwong, Org. Lett., 2009, 11, 317-320.


Key Words

Suzuki Coupling, Biaryls


ID: J42-Y2010-2110