Synthesis of N-Arylindazoles and Benzimidazoles from a Common Intermediate
Brenda C. Wray and James P. Stambuli*
*Evans Chemical Laboratories, Department of Chemistry, The
Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, Email:
stambuli
chemistry.ohio-state.edu
B. C. Wray, J. P. Stambuli, Org. Lett., 2010, 12, 4576-4579.
DOI: 10.1021/ol101899q
Abstract
Various N-aryl-1H-indazoles and benzimidazoles were synthesized from common arylamino oximes in good to excellent yields depending upon the base used in the reaction. Triethylamine promoted the formation of benzimidazoles, whereas 2-aminopyridine promoted the formation of N-arylindazoles.
see article for more examples
Key Words
ID: J54-Y2010-2860
