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Gold(I)-Catalyzed Cycloisomerization of β-Alkynylpropiolactones to Substituted α-Pyrones

Thomas Dombray, Aurélien Blanc*, Jean-Marc Weibel and Patrick Pale*

*Laboratoire de Synthèse et Réactivité Organiques Associé au CNRS, Institut de Chimie, Université de Strasbourg, 4 rue Blaise Pascal, 67000 Strasbourg, France, Email: ablancunistra.fr, ppaleunistra.fr

T. Dombray, A. Blanc, J.-M. Weibel, P. Pale, Org. Lett., 2010, 12, 5362-5365.

DOI: 10.1021/ol103739 (free Supporting Information)


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Abstract

A gold(I)-catalyzed rearrangement of β-alkynylpropiolactones enables a straightforward synthesis of substituted α-pyrones in good yields.

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Key Words

2-Pyrones


ID: J54-Y2010-3320