Versatile and Iodine Atom-Economic Co-Iodination of Alkenes
Himabindu Gottam and Thottumkara K. Vinod*
*Department of Chemistry, Western Illinois University, Macomb, Illinois 61455, United States, Email: tk-vinodwiu.edu
H. Gottam, T. K. Vinod, J. Org. Chem., 2011, 76, 974-977.
DOI: 10.1021/jo102051z (free Supporting Information)
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Acetyl hypoiodite (CH3CO2I) is readily generated in situ by oxidation of molecular iodine by (diacetoxyiodo)benzene (DAIB) and can be utilized for the synthesis of 1,2-iodo-cofunctionalized derivatives of alkenes. Conversion of both atoms of molecular iodine to I+ results in 100% iodine atom economy for the reported iodo-cofunctionalization of alkenes.
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