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Facile Synthesis of (E)-Alkenyl Aldehydes from Allyl Arenes or Alkenes via Pd(II)-Catalyzed Direct Oxygenation of Allylic C-H Bond

Huoji Chen, Huanfeng Jiang*, Congbi Cai, Jia Dong and Wei Fu

*School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China, Email: jianghfscut.edu.cn

H. Chen, H. Jiang, C. Cai, J. Dong, W. Fu, Org. Lett., 2011, 13, 992-994.

DOI: 10.1021/ol1030316 (free Supporting Information)


Abstract

Palladium-catalyzed oxygenation of allyl arenes or alkenes produce (E)-alkenyl aldehydes with high yields. Allylic C-H bond cleavages occur under mild conditions during this process. Mechanistic studies show that oxygen source is water.

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Key Words

Aldehydes, Enones, DDQ


ID: J54-Y2011-0450