Catalytic Enantioselective Conjugate Allylation of Unsaturated Methylidene Ketones
Laura A. Brozek, Joshua D. Sieber and James P. Morken*
*Department of Chemistry, Merkert Chemistry Center, Boston
College, Chestnut Hill, Massachusetts 02467, United States, Email: morken
bc.edu
L. A. Brozek, J. D. Sieber, J. P. Morken, Org. Lett., 2011, 13, 995-997.
DOI: 10.1021/ol102982b
Abstract
The use of unsaturated methylidene ketones in catalytic conjugate allylations allows a significant expansion in substrate scope and, with appropriate chiral ligands, occurs in a highly enantioselective fashion.
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Key Words
Conjugate Addition, Allylation
ID: J54-Y2011-0470
