Organic Chemistry Portal

Abstracts

Search:

Palladium- and Nickel-Catalyzed Aminations of Aryl Imidazolylsulfonates and Sulfamates

Lutz Ackermann*, Rene Sandmann and Weifeng Song

*Institut fur Organische und Biomolekulare Chemie, Georg-August-Universitat, Tammannstrasse 2, 37077 Gottingen, Germany, Email: Lutz.Ackermannchemie.uni-goettingen.de

L. Ackermann, R. Sandmann, W. Song, Org. Lett., 2011, 13, 1784-1786.

DOI: 10.1021/ol200267b (free Supporting Information)


see article for more reactions

Abstract

A nickel complex derived from dppf, along with NaOt-Bu as the base, enabled challenging aminations of aryl sulfamates. Palladium-catalyzed aminations of imidazolylsulfonates with rac-BINAP as the ligand offer an improved functional group tolerance.

see article for more examples



Key Words

Arylamines, Buchwald-Hartwig Coupling


ID: J54-Y2011-0900