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Cu(I)-Catalyzed Domino Reactions: Efficient and Selective Synthesis of 4H-Chromenes and Naphthalenes

Chandi C. Malakar, Dietmar Schmidt, Jürgen Conrad and Uwe Beifuss*

*Institut fur Chemie, Universitat Hohenheim, Garbenstr. 30, 70599 Stuttgart, Germany, Email: ubeifussuni-hohenheim.de

C. C. Malakar, D. Schmidt, J. Conrad, U. Beifuss, Org. Lett., 2011, 13, 1972-1975.

DOI: 10.1021/ol200347g (free Supporting Information)


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Abstract

A Cu(I)-catalyzed domino reaction between bromobenzyl bromides and β-ketoesters exclusively yields either 4H-chromenes or naphthalenes depending on the ratio of the substrates and the reaction conditions.

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Key Words

4H-Chromenes


ID: J54-Y2011-1040