Organic Chemistry Portal

Abstracts

Search:

An Efficient Protocol for the Synthesis of 2-Phenylquinazolines Catalyzed by Ceric Ammonium Nitrate (CAN)

K. Karnakar, J. Shankar, S. Narayana Murthy, K. Ramesh, Y. V. D. Nageswar*

*Organic Chemistry Division I, Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad 500607, India, Email: dryvdnageswargmail.com

K. Karnakar, J. Shangkar, S. N. Murthy, K. Ramesch, Y. V. D. Nageshwar, Synlett, 2011, 1089-1096.

DOI: 10.1055/s-0030-1259960 (free Supporting Information)


Abstract

A facile and efficient method for the synthesis of 2-phenylquinazolines from 2-aminobenzophenones and benzylamines is catalyzed by ceric ammonium nitrate (CAN)-TBHP in acetonitrile. The corresponding 2-phenylquinazolines were obtained in good to excellent yields.

see article for more examples



Key Words

quinazolines, 2-aminobenzophenones, benzylamines, ceric ammonium nitrate, tert-butyl hydroperoxide, acetonitrile


ID: J60-Y2011-1260