Copper-Catalyzed Trifluoromethylation of Aryl and Vinyl Boronic Acids with An Electrophilic Trifluoromethylating Reagent
Tianfei Liu and Qilong Shen*
*Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, People's Republic of China, Email: shenqlmail.sioc.ac.cn
T. Liu, Q. Shen, Org. Lett., 2011, 13, 2342-2345.
DOI: 10.1021/ol2005903
Abstract
A copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with Togni's reagent proceeded in good to excellent yields for a range of different substrates including heteroarylboronic acids and substrates with a variety of functional groups under mild reaction conditions.
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Key Words
trifluoromethylation of arenes
ID: J54-Y2011-1340