A Facile and Efficient Synthesis of 2-Imidazolines from Aldehydes Using Hydrogen Peroxide and Substoichiometric Sodium Iodide
Guo-yi Bai*, Kai Xu, Guo-feng Chen, Yong-hui Yang, Tian-yu Li
*Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, P. R. of China , Email: gybaihbu.edu.cn
G.-y. Bai, K. Xu, G.-f. Chen, Y.-h. Yang, T.-y. Li, Synthesis, 2011, 1599-1603.
A mild, environmentally friendly, and efficient process enables the synthesis of 2-imidazolines in high yield by reaction of aldehydes with ethylenediamine using hydrogen peroxide as an oxidant in the presence of sodium iodide and anhydrous magnesium sulfate.
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