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Silver Triflate Catalyzed Acetylation of Alcohols, Thiols, Phenols, and Amines

Rima Das, Debashis Chakraborty*

*Department of Chemistry, Indian Institute of Technology Madras, Chennai-600 036, Tamil Nadu, India , Email:

R. Das, D. Chakraborty, Synthesis, 2011, 1621-1625.

DOI: 10.1055/s-0030-1259999


Various alcohols, thiols, phenols, and amines can be acetylated using acetic anhydride in the presence of catalytic quantity of silver triflate. The method proceeds under mild conditions, does not involve cumbersome workup, and the resulting products are obtained in high yields within a reasonable time.

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Key Words

acetylation (alcohols, phenols, thiols, amines), acetamides, acetic acid esters, silver triflate

ID: J66-Y2011-1500