A Simple and Efficient Protocol to 1,2,4-Substituted Pyrroles via a Sonogashira Coupling-Acid-Catalyzed Cyclization
Da Zhu, Jie Zhao, Yuxiu Wei, Hongwei Zhou*
*Department of Chemistry, Zhejiang University, (Campus Xixi),
Hangzhou 310007, P. R. of China, Email: zhouhw
zju.edu.cn
D. Zhu, J. Zhao, Y. Wei, H. Zhou, Synlett, 2011, 2185-2186.
DOI: 10.1055/s-0030-1261175
Abstract
A facile and efficient protocol enabled the synthesis of 1,2,4-substituted pyrrole derivatives from ready available starting materials. This type of reaction should have potential utility in organic synthesis.
see article for more examples
Key Words
pyrroles, Sonogashira coupling, gallium triflate, cyclization, 2-bromoallylamine
ID: J60-Y2011-2610
