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Ligand-Promoted, Copper Nanoparticles Catalyzed Oxidation of Propargylic Alcohols with TBHP or Air as Oxidant

Chengyan Han, Min Yu, Weijiang Sun, Xiaoquan Yao*

*Department of Applied Chemistry, School of Material Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, P. R. of China, Email: yaoxqnuaa.edu.cn

C. Han, M. Yu, W. Sun, Y. Yao, Synlett, 2011, 2363-2368.

DOI: 10.1055/s-0030-1261227 (free Supporting Information)


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Abstract

A highly efficient oxidation of propargylic alcohols to ynones is catalyzed by copper nanoparticles (Cu Nps) with TBHP or air as oxidants. With bipyridine as the ligand, the reaction was accelerated significantly and led in good to excellent yields to a variety of propargylic alcohols.

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Key Words

propargylic alcohols, oxidation, ynones, copper nanoparticles, ligand effect, TBHP


ID: J60-Y2011-2830