Polyethylene Glycol (PEG-400) as an Efficient and Recyclable Reaction Medium for the One-Pot Synthesis of N-Substituted Azepines under Catalyst-Free Conditions
Raghu Mallepalli, Lingappa Yeramanchi, Rajashaker Bantu, Lingaiah Nagarapu*
*Organic Chemistry Division-II, Indian Institute of Chemical Technology, Hyderabad 500 607, India, Email: lnagarapuiictyahoo.com
R. Mallepalli, L. Yeramanchi, R. Bantu, L. Nagarpu, Synlett, 2011, 2730-2732.
DOI: 10.1055/s-0031-1289542 (free Supporting Information)
Polyethylene glycol (PEG) is an inexpensive nontoxic and effective medium for the one-pot synthesis of N-substituted azepines under catalyst-free conditions in excellent yields. Environmental acceptability, low cost, high yields, and recyclability of the PEG are the important features of this protocol.
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