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Triflic Acid Catalyzed Oxidative Lactonization and Diacetoxylation of Alkenes Using Peroxyacids as Oxidants

Yan-Biao Kang and Lutz H. Gade*

*Catalysis Research Laboratory (CaRLa), Im Neuenheimer Feld 584, 69120 Heidelberg, Germany, Email: lutz.gadeuni-hd.de

Y.-B. Kang, L. H. Gade, J. Org. Chem., 2012, 77, 1610-1615.

DOI: 10.1021/jo202491y (free Supporting Information)


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Abstract

A clean and efficient and metal-free diacetoxylation reaction of alkenes using commercially available peroxyacids as the oxidants is catalyzed by triflic acid. This method enables also oxidative lactonizations of unsaturated carboxylic acids in good to high yields.

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Key Words

1,2-Diols, MCPBA, Peracetic Acid, Green Chemistry


ID: J42-Y2012-0240