Organic Chemistry Portal

Abstracts

Search:

Efficient Palladium-Catalyzed Cross-Coupling Reaction of Alkynyl Halides with Organoboronic Acids under Aerobic Conditions

Jian-Sheng Tang*, Mi Tian, Wen-Bing Sheng, Can-Cheng Guo*

*College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. of China, Email: ccguohnu.edu.cn, hnyztjs163.com

J.-S. Tang, M. Tian, W.-B. Sheng, C.-C. Guo, Synthesis, 2012, 44, 541-546.

DOI: 10.1055/s-0031-1290159 (free Supporting Information)



see article for more reactions

Abstract

In the presence of bis(dibenzylideneacetone)palladium(0) and cesium carbonate, a variety of alkynyl halides underwent a ligand-free Suzuki-Miyaura cross-coupling reaction with organoboronic acids at room temperature under aerobic conditions to afford the corresponding unsymmetrical diarylalkynes in good yields.

see article for more examples



Key Words

palladium, alkynyl halides, organoboronic acids, cross-coupling reaction, alkynes, Suzuki Coupling


ID: J66-Y2012-0370