Chiral Brønsted Acid Catalyzed Enantioselective Propargylation of Aldehydes with Allenylboronate
Leleti Rajender Reddy*
*Chemical and Analytical Development, Novartis Pharmaceutical
Corporation, East Hanover, New Jersey 07936, United States, Email:
Email: reddylrajender
yahoo.com
L. R. Reddy, Org. Lett., 2012, 14, 1142-1145.
DOI: 10.1021/ol300075n
Abstract
A highly enantioselective chiral Brønsted acid catalyzed propargylation of aldehydes with allenylboronate allows a practical conversion of a broad range of substrate covering aryl, polyaryl, heteroaryl, α,β-unsaturated, and aliphatic aldehydes.
see article for more examples
Key Words
ID: J54-Y2012-0480
