Palladium-Catalyzed Direct Hydroxymethylation of Aryl Halides and Triflates with Potassium Acetoxymethyltrifluoroborate
Norio Murai, Masahiro Yonaga* and Keigo Tanaka*
*Discovery Research Laboratories, Eisai Co., Ltd., 5-1-3
Tokodai, Tsukuba, Ibaraki 300-2635, Japan, Email: k6-tanaka
hhc.eisai.co.jp,
m-yonagahhc.eisai.co.jp
N. Murai, M. Yonaga, K. Tanaka, Org. Lett., 2012, 14, 1278-1281.
DOI: 10.1021/ol300149b
Abstract
Suzuki-Miyaura cross-coupling of aryl halides and triflates with potassium acetoxymethyltrifluoroborate afforded the corresponding benzylic alcohols in good yields.
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Key Words
ID: J54-Y2012-0620
