Cu(acac)2-Catalyzed Synthesis of Functionalized Bis(arylmethyl)zinc Reagents and Their Olefination Reaction with Aromatic Aldehydes
Ying Fu*, Xuemei Hu, Yaojuan Chen, Yanshou Yang, Hongxia Hou, Yulai Hu
*College of Chemistry and Chemical Engineering, Northwest
Normal University, Lanzhou, 730070, P. R. of China, Email: fuying
iccas.ac.cn
Y. Fu, X. Hu, Y. Chen, Y. Yang, H. Hou, Y. Hu, Synthesis, 2012, 44, 1030-1036.
DOI: 10.1055/s-0031-1289723
Abstract
An efficient and facile copper(II) acetylacetonate catalyzed synthesis of functionalized bis(arylmethyl)zinc reagents from arylmethyl halides followed by olefination with aromatic aldehydes gives (E)-stilbenes in good yields. Aluminum trichloride was found to be the key ingredient in these reactions.
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Key Words
aldehydes, zinc, nucleophilic addition, olefination, benzylation, stilbenes
ID: J66-Y2012-1290
