Indium Tri(isopropoxide)-Catalyzed Selective Meerwein-Ponndorf-Verley Reduction of Aliphatic and Aromatic Aldehydes
Jaeyoung Lee, Taekyu Ryu, Sangjune Park and Phil Ho Lee*
*Department of Chemistry, Kangwon National University, Chuncheon 200-701, Republic of Korea, Email: phleekangwon.ac.kr
J. Lee, T. Ryu, S. Park, P. H. Lee, J. Org. Chem., 2012, 77, 4821-4825.
DOI: 10.1021/jo300236u (free Supporting Information)
Indium tri(isopropoxide)-catalyzed Meerwein-Ponndorf-Verley reduction of aliphatic and aromatic aldehydes in 2-propanol gave selectively the corresponding primary alcohols in good to excellent yields at room temperature. The reaction tolerates a wide range of functional groups including alkene, ether, ketone, ester, nitrile, and nitro.
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