Effect of Chiral Diene Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to α,β-Unsaturated Sulfonyl Compounds
Takahiro Nishimura*, Yuka Takiguchi and Tamio Hayashi*
*Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan, Email: tnishikuchem.kyoto-u.ac.jp, thayashikuchem.kyoto-u.ac.jp
T. Nishimura, Y. Takiguchi, T. Hayashi, J. Am. Chem. Soc., 2012, 134, 9086-9089.
DOI: 10.1021/ja303109q
Abstract
Asymmetric addition of arylboronic acids to α,β-unsaturated sulfonyl compounds proceeded in the presence of a rhodium catalyst coordinated with a chiral diene ligand to give high yields of the addition products with high enantioselectivity. The diene ligand was proved to be essential for the formation of the addition products.
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Key Words
ID: J48-Y2012-1690