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Cobalt-Catalyzed Vinylation of Aromatic Halides Using β-Halostyrene: Experimental and DFT Studies

Aurélien Moncomble, Pascal Le Floch, Agusti Lledos and Corinne Gosmini*

*Laboratoire Hétéroéléments et Coordination, Ecole Polytechnique, CNRS, Route saclay, 91128 Palaiseau Cedex, France, Email: corinne.gosminipolytechnique.edu

A. Moncomble, P. Le Floch, A. Lledos, C. Gosmini, J. Org. Chem., 2012, 77, 5056-5062.

DOI: 10.1021/jo3005149 (free Supporting Information)


Abstract

A direct cobalt-catalyzed vinylation of various aromatic halides using β-halostyrene proceeded smoothly with a total retention of the double bond configuration in the presence of triphenylphosphine as ligand. This procedure offers a new route to the stereoselective synthesis of functionalized stilbenes.

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Key Words

Stilbenes, Manganese


ID: J42-Y2012-1710