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Robust Acenaphthoimidazolylidene Palladium Complexes: Highly Efficient Catalysts for Suzuki-Miyaura Couplings with Sterically Hindered Substrates

Tao Tu*, Zheming Sun, Weiwei Fang, Mizhi Xu and Yunfei Zhou

*Department of Chemistry, Fudan University, 220 Handan Road, 200433, Shanghai, China, Email: taotufudan.edu.cn

T. Tu, Z. Sun, W. Fang, M. Xu, Y. Zhou, Org. Lett., 2012, 14, 4250-4253.

DOI: 10.1021/ol3019665 (free Supporting Information)


Abstract

Robust acenaphthoimidazolylidene palladium complexes are highly efficient and general catalysts the Suzuki-Miyaura cross-coupling reactions of sterically hindered substrates in excellent yields with low catalyst loadings under mild conditions. Both the "flexible steric bulk" concept and σ-donor properties of the NHC ligands are crucial for the high catalytic activity of these complexes.

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Key Words

Suzuki Coupling


ID: J54-Y2012-2650