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FeCl36H2O-Catalyzed Intramolecular Allylic Amination: Synthesis of Substituted Dihydroquinolines and Quinolines

Zhiming Wang*, Shen Li, Bin Yu, Haibo Wu, Yurong Wang and Xiaoqiang Sun*

*School of Petrochemical Engineering, Changzhou University, Changzhou, Jiangsu 213164, China, Email:,

Z. Wang, S. Li, B. Wu, Y. Wang, X. Sun, J. Org. Chem., 2012, 77, 8615-8620.

DOI: 10.1021/jo301560w (free Supporting Information)

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A facile and efficient iron-catalyzed intramolecular allylic amination of 2-aminophenyl-1-en-3-ols proceeded smoothly to afford 1,2-dihydroquinoline and quinoline derivatives under mild reaction conditions with good yields.

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Key Words

1,2-dihydroquinolines, quinolines

ID: J42-Y2012-3210